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PGD – Pre-implantation Genetic Diagnosis

Preimplantation genetic screening is a method utilized to determine genetic problems in embryos developed through in Vitro Fertilization (IVF) before pregnancy. Preimplantation genetic diagnosis (PGD) makes reference particularly to when one or both genetic mother and father have a known genetic abnormality and examining is performed on an embryo to figure out if additionally, it carries a genetic abnormality.

For the reason that only unaffected embryos are transmitted to the womb for implantation, preimplantation genetic analyzing allows a alternative to current post getting conceived diagnostic treatments, which are regularly observed by the challenging alternatives of pregnancy cancellations if results are negative. PGD and PGS are currently the only possibilities accessible for preventing a high risk of getting a child impacted which has a genetic disease before implantation. It is an appealing indicates of protecting against heritable genetic illness, thereby getting rid of the dilemma of pregnancy cancellations right after undesirable prenatal examination.

This kind of genetic screening is carried out on eggs or embryos while in an in vitro fertilization (IVF) period. The eggs or embryos which may have been examined and are identified to be regular are transferred into the woman’s womb, where by ideally, they are going to enhancement and cause the birth of a healthy and balanced child.

How could PGD assist me?

PGD can considerably minimize the probabilities to your baby to be affected with a specific genetic issue or genetic problem. Surya Fertility Centre has the ability to test for several various health conditions, which includes aneuploidy, single gene diseases and chromosome translocations.

A lot of couples ask for PGD for aneuploidy just like Down syndrome, trisomy 18, trisomy 13 and Turner syndrome. These conditions do not commonly run in family members. Even so, approximately 60% of earlier miscarriages are due to aneuploidy, as well as the risk for aneuploidy raises with a woman’s age. The objective of PGD for aneuploidy will be to maximize a couple’s possibility for pregnancy, cut down their risk for miscarriage, and improve their overall likelihood of getting home a healthy child following  In Vitro Fertilization(IVF).

Other married couples inquire PGD for a certain genetic problem which may run in their family, such as Tay Sachs disease, cystic fibrosis, muscular dystrophy, Fragile X syndrome or spinal muscular atrophy. Our center has extensive experience testing for many single gene disorders, as well as rare genetic syndromes.

For individuals who carry a chromosomal translocation, PGD can be used to test eggs or embryos for their specific translocation. This greatly decreases the risk for miscarriage and/or the birth of a child with birth defects and mental retardation associated with an unbalanced chromosome translocation. We can also test for the HLA status of embryos. This is requested by couples interested in having a child who is a healthy bone marrow match to another family member. HLA testing can be performed while testing for a specific genetic condition, such as beta-Thalassemia.

What conditions are tested with PGD?

The conditions tested include aneuploidy, single gene disorders, and translocations.

How is PGD performed?

Embryo Analysis is the commonly used method for PGD.

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